Review Note
Last Update: 02/18/2024 05:30 AM
Current Deck: Part 2::1. Subsites::CNS::High grade glioma (Adult)
Published
Fields:
Site
Histology
Epidemiology (1.1 Incidence in population; 1.2 Age of onset; 1.3 Gender prediliction, 1.4 Geographical distribution
Aetiology (individual causative factors) and pathogenesis 2.1 Genetic/chromosomal abnormalities; 2.2 Environmental; 2.3 Nonhereditary predisposing conditions; 2.4 Associated familial cancer syndromes
Natural history. 3.1 Precursor lesions. 3.2 Field effect. 3.3 Patterns of spread and biological behaviour
Clinical presentation. 4.1. Common symptoms and signs - link to pathology
Clinical presentation. 4.2. Effects of tumour on the host - 4.2.1 paraneoplastic syndromes, 4.2.2 cancer cachexia, 4.2.3 local effects e.g. destruction of adjacent tissues, 4.2.4 hormonal effects
Clinical presentation. 4.3. Characteristic imaging findings - link to pathology
Macroscopic appearance and growth patterns (5.1)
Microscopic. 5.2.1 Histological subtypes and classifications. 5.2.2 Link to predicted biological behaviour
Microscopic. 5.2.3 Laboratory methods, including frozen section analysis and electron microscopy
Microscopic. 5.2.4 Characteristic cellular appearance and architecture
Microscopic. 5.2.5 Grading systems
Microscopic. 5.2.6 Immunohistochemistry
Microscopic. 5.2.7 Molecular techniques, chromosomal changes, flow cytometry
Microscopic. 5.2.8 Uncertainty in microscopic diagnosis
5.3 Normal histology and structure of tissue of origin, i.e. distinguish normal from pathological areas
5.4 Differential diagnosis i.e. other histologies to consider in relation to the anatomical location
Staging and classification systems - 6.1 TNM principles and terminology; 6.2 Commonly applied staging systems; 6.3 Commonly applied classification systems
Prognostic and predictive factors
Outcomes - Tumour Discuss the risk of relapse and typical time course (including range) for relapse dependent on risk factors for failure
Additional question 1
Answer to additional question 1
Additional question 2
Answer to additional question 2
Additional question 3
Answer to additional question 3
Additional question 4
Answer to additional question 4
Additional question 5
Answer to additional question 5
Additional question 6
Answer to additional question 6
Additional question 7
Answer to additional question 7
Additional question 8
Answer to additional question 8
Suggested Changes:
Deck Changes (Suggestion to move the Note to the following Deck):
Field Changes:
Tag Changes: