Review Note

Last Update: 02/18/2024 05:30 AM

Current Deck: Part 2::6. High Yield Questions::Genitourinary

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Front
A 65-year-old man presents with a PSA of 0.3 mcg/L 12 months after a radical 
prostatectomy. His initial pathology showed adenocarcinoma (Gleason 4+5) with 
extracapsular extension and a positive margin. 

Describe a suitable radiation therapy technique and dose fractionation schedule for this 
patient. 
Back
Presim: 
o   Review pathology, PSAs, imaging, MRI 
o   pelvic floor training 
o   Commence short term ADT 

Simulation 
o   Position – supine, arms on chest 
o   Immobilization: neck support, knee supports, ankle stocks 
o   Bladder full, rectum empty- protocol (rescan if rectum >4cm diam) 
o   CT scan – 3DCT from L3/4 (ASIS) 1.5cm below ischial tuberosities 

Dose: 68Gy/34# to the prostate bed, 56Gy/34# to the pelvic nodes in a SIB technique
o   9 fractions per fortnight 
o   VMAT 6/10 MV photons 

Target volumes
CTV: Surgical bed 
  • Inf border of CTV is 5mm below anastomosis  
  • Ant= posterior aspect of pubic symphisis for inferior 3cm of volume, then posterior 1.5cm of bladder wall 
  • Post= Space delineated by levator ani + anterior rectal wall. 
  • Lat= medial border of levator ani/obturator internus 
  • Sup= superior vascular clip, or inferior portion of vas deferens.  
PTV= CTV+ 7mm 

CTV nodes = obturator nodes, external, internal iliac, presacral lymphnodes.
PTV = CTV+5mm

OAR constraints 
  • Rectum 
    • V40<60%
    • V50<50%
    • V60<40%
    • V66<30%
  • Bladder 
    • V40<50%
    • V65<25% 
  • Femoral heads 
    • V50<5%
    • V60<30%
    • V45Gy<60%
  • Penile bulb: Mean <52.5Gy
  • Small bowel: 
    • 2cc <60Gy, 100cc <45Gy (cavity) 
Further information, not for memorising (no card)
Exam

Current Tags:

#prostate #Radiotherapy

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