Review Note
Last Update: 02/18/2024 05:30 AM
Current Deck: Part 2::6. High Yield Questions::Genitourinary
PublishedCurrently Published Content
Front
iii. List the patient and treatment factors that may
influence risk of radiation induced malignanc. (1.5)
Back
Factors that cause increased risk
Patient related factors:
- younger age
- organs exposed to radiation
- Highest risk: bone marrow, breast ,salivary gland, thyroid
- Next highest: lung, stomach, rectum, bladder
- environmental exposure: smoking, dietary (high nitrites), chemicals - synergistic effect with radiation exposure
- Genetic predispositions: Retinoblastoma, ataxia talengiectasia, chronic inflammatory diseases
Treatment related factors:
- higher dose
- higher dose rate
- larger volume irradiated, including higher integral dose
- high LET radiation
- concurrent treatment with chemotherapy, or other radiosensitisers.
Patient related factors:
- younger age
- organs exposed to radiation
- Highest risk: bone marrow, breast ,salivary gland, thyroid
- Next highest: lung, stomach, rectum, bladder
- environmental exposure: smoking, dietary (high nitrites), chemicals - synergistic effect with radiation exposure
- Genetic predispositions: Retinoblastoma, ataxia talengiectasia, chronic inflammatory diseases
Treatment related factors:
- higher dose
- higher dose rate
- larger volume irradiated, including higher integral dose
- high LET radiation
- concurrent treatment with chemotherapy, or other radiosensitisers.
Further information, not for memorising (no card)
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