Review Note
Last Update: 02/28/2024 08:31 PM
Current Deck: Step 2::Mehlman::Mehlman Ob Gyn
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Text
Neonatal girl with karyotype 46XX + has phallus and scrotum; Q asks mechanism = {{c1::ACTH hypersecretion}}
Extra
in congenital adrenal hyperplasia caused by 21- and 11-hydroxylase deficiency, cortisol is low, so ACTH goes up to compensate, leading to cortical hyperplasia; in addition, precursors are shunted to DHEA-S and androsteredione, leading virilization of newborn
Lecture Notes
Missed Questions
Pathoma
Boards and Beyond
First Aid
Sketchy
Pixorize
Physeo
OME
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