Review Note
Last Update: 03/15/2024 10:45 AM
Current Deck: Collab4PG
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Hypoxia-induced vasoconstriction in pulmonary circulation results due to the inhibition of the {{c1::oxygen-sensitive potassium}} channel.
Extra
-> depolarization of the cell membrane
-> activation of calcium channels causing the influx of calcium ions.
-> constriction of small arteries and arterioles.
-> activation of calcium channels causing the influx of calcium ions.
-> constriction of small arteries and arterioles.
Lecture Notes
Missed Questions
Pathoma
When the concentration of O2 in the alveoli decreases below normal the adjacent blood vessels constrict. This effect is opposite to the effect observed in systemic vessels, which dilate rather than constrict in response to low O2 levels.
This is because the low oxygen concentrations can
- Stimulate the release of or increase sensitivity to vasoconstrictor substances such as endothelin or reactive oxygen species.
- Decrease the release of vasodilators such as nitric oxide from the lung.
Boards and Beyond
First Aid
Sketchy
Sketchy 2
Sketchy Extra
Picmonic
Pixorize
Physeo
Bootcamp
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