Review Note

Last Update: 03/18/2024 02:13 AM

Current Deck: CH-Deakin-Ben

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Definition and pathophysiology of Anaphylaxis
Multi-system severe allergic response characterised by cardiovascular & respiratory symptoms. 

Type I hypersensitivity reaction, immedidate reaction involving IgE mediated amine, lipid mediator and cytokine release.

Hypersensitivity Type I: Mechanism and Clinical Manifestation • Microbe  Online
allergein binds + B cell which presents to Th2 cell --> IgE secreting B cell --> Ige + mast cell --> vasoreactive amines + lipid mediators + cytokines