Review Note

KIDNEY FUNCTION
Helps maintain {{c1::homeostasis}}
1) By {{c2::excreting waste products of metabolism}}
a. Urea, creatinine, and uric acid, etc.
2) By {{c2::adjusting the urinary excretion of water and electrolytes to match net intake and endogenous production}}
a. In a healthy kidney, blood levels of {{c3::electrolytes and fluid}} balance is maintained in a {{c3::narrow}} range whereas the amount of {{c3::fluid and electrolytes}} in the urine can vary {{c3::widely.}}

- The kidney is able to regulate individually the excretion of water and solutes such as sodium, potassium, and hydrogen, largely by changes in tubular reabsorption or secretion.
• The assessment of the kidneys ability to perform this task is based in estimating the {{c4::FLOW rate of the kidney (GFR)}}

- It secretes hormones that participate in the regulation of systemic and renal
hemodynamics (renin, prostaglandins, and bradykinin), red blood cell production
(erythropoietin), and calcium, phosphorus, and bone metabolism (1,25-
dihydroxyvitamin D3 or calcitriol).