Review Note

Last Update: 04/01/2024 02:30 AM

Current Deck: Neurology::Neuropathology

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What condition is this path slide consistent with? {{c1::Tumefactive MS}}
Notes
Tumefactive MS
  • Histopathology:
    • Macrophages: Sheets, typical of demyelinating lesion
  • Patient Presentation:
    • Solitary mass lesion
  • Diagnosis:
    • Tumefactive demyelinating lesion
    • Likely a form of Multiple Sclerosis (MS)
  • Neuroimaging Clues:
    • Incomplete ring: Demyelinative lesions
    • Complete ring: Glioblastoma or brain abscess
  • Cellular Analysis:
    • Macrophages: Foamy cytoplasm with phagocytosed myelin debris
    • Exclusion: Oligodendroglioma, renal cell carcinoma
  • Additional Findings:
    • Absence: Neoplastic cells, neutrophils (typical of brain abscess)
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