Review Note
Last Update: 04/01/2024 02:30 AM
Current Deck: Neurology::Neuropathology
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![](quizlet-WMCXwiWWU-YoIUZqot3OzA.png)
What condition is this path slide consistent with? {{c1::Tumefactive MS}}
Notes
Tumefactive MS
- Histopathology:
- Macrophages: Sheets, typical of demyelinating lesion
- Patient Presentation:
- Solitary mass lesion
- Diagnosis:
- Tumefactive demyelinating lesion
- Likely a form of Multiple Sclerosis (MS)
- Neuroimaging Clues:
- Incomplete ring: Demyelinative lesions
- Complete ring: Glioblastoma or brain abscess
- Cellular Analysis:
- Macrophages: Foamy cytoplasm with phagocytosed myelin debris
- Exclusion: Oligodendroglioma, renal cell carcinoma
- Additional Findings:
- Absence: Neoplastic cells, neutrophils (typical of brain abscess)
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