Review Note
Last Update: 04/01/2024 02:30 AM
Current Deck: Neurology::Other
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Pathophysiology of Alexander disease:
- Disrupted dimerization of {{c1::GFAP}} causing cytoskeletal collapse and protein aggregation
- GFAP gene provides instructions for {{c2::making a protein called glial fibrillary acidic protein. }}
- This protein is a member of the intermediate filament family of proteins.
- Intermediate filaments form networks that {{c2::provide support and strength to cells. }}
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