Review Note
Last Update: 04/01/2024 02:31 AM
Current Deck: Neurology::Prior Rite Questions
PublishedCurrently Published Content
Text
A 2-year-old boy has had seizures since age 9 months. Initially, most episodes were characterized by prolonged hemiclonic seizures that coincided with fever. The parents now report seizures can be triggered by hot or warm baths. "Staring off" spells and myoclonic jerks have also emerged lately. For the past couple months, he has missed his development milestones. Which of the following antiseizure medications is contraindicated?
- cannabidiol
- topiramate
- Lamotrigine
- clobiazam
- valproic acid
Answer: {{c1::Lamotrigine}}
Notes
his case is suggestive of Dravet syndrome, a severe form of epilepsy that begins in infancy. Lamotrigine is contraindicated in patients with Dravet syndrome because it can exacerbate seizures in these individuals.
Analysis of Incorrect Answers:
- Cannabidiol: This is incorrect because cannabidiol is actually one of the few effective treatments for Dravet syndrome and has been approved by the FDA for this indication.
- Topiramate: This is also incorrect because topiramate can be used in the management of Dravet syndrome and does not exacerbate seizures.
- Clobiazam: This is incorrect because clobiazam is often used as an adjunctive treatment in Dravet syndrome and has been shown to reduce seizure frequency.
- Valproic acid: This is incorrect because valproic acid is a commonly used antiseizure medication in Dravet syndrome and can be effective in controlling seizures.
Mnemonic
Images
Related Videos
Missed Questions
One by one
Current Tags:
Pending Suggestions
No pending suggestions for this note.