Review Note

Last Update: 04/01/2024 02:31 AM

Current Deck: Neurology::RITE Images

Published

What does this image show? {{c1::Ependymoma}}

Ependymoma Is the best response for this surgically proven case. The presence of a well-defined intramedullary mass with contrast enhancement, T2 hyperintensity and T1 hypointensity in the cord, cystic components adjacent to the solid enhancing portions of the tumor are typical. Also typical is subtle T2 hypointensity along the margins of the well-defined solid portion of the tumor
Perivascular pseudorosettes are seen in ependymomas
Ependymomas in the supratentorial region occur in the periventricular region, but they may uncommonly be more superficial. Ependymomas can also occur in the spinal cord, more commonly in adults
Most ependymomas are WHO grade II. Anaplastic ependymomas are graded as WHO III, and are characterized by the presence of increased mitotic activity, hypercellularity, and microvascular proliferation. WHO grade II ependymomas may be surgically curable with a good prognosis, being the extent of resection an important prognostic factor. Radiation therapy may be used for residual disease. Prognosis is worse in patients younger than 3 years of age at presentation.
Ependymomas in contact with the CSF may produce drop metastases conferring a worse prognosis.