Review Note

Last Update: 04/01/2024 06:38 AM

Current Deck: Spring 2024 P1 Semester::Spring 2024 IE #5::Pharm 212 Local Anesthetics

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“CAIN” ALTERNATIVES WITH LOCAL ANESTHETIC ACTIVITY (LESS ALLERGY)

1) {{c1::Diphenhydramine}}
  • {{c2::first-generation, sedating, oral antihistamine}}
  • {{c2::DPH 1%}} solution is a safe, effective, inexpensive alternative to “caine” local anesthetics
  • allows {{c2::same-day surgery}} in patients 
    • with a {{c3::history of “caine” anesthetic reactions }}
    • with a {{c3::questionable history without definitive allergy testing}}
  • Metabolism: {{c4::Liver}} 
  • Excretion: {{c4::Urine and feces}}
2) {{c1::promethazine}}
  • {{c5::phenothiazine}} that can treat {{c6::allergies}} and {{c6::motion sickness}}
  • used as a {{c5::sedative}} {{c7::before}} and {{c7::after}} surgery and medical procedures
  • help control {{c8::pain}}, {{c8::nausea}}, and {{c8::vomiting}}.
  • metabolism: {{c9::liver}}
  • excretion: {{c9::kidney}} and {{c9::biliary}} 

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