Review Note
Last Update: 05/12/2024 04:45 AM
Current Deck: Clin Med::Renal::Electrolyte Disturbances: Na+, K+
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what does it mean if you have hyponatremia with HIGH serum osmolality?
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Hypertonic hyponatremia
1. hyperglycemia → DKA
Hyponatremia with high serum osmolality (hypERosmolar) → result of elevated levels of an extra solute in the plasma that does not readily enter cells → This draws water into the extracellular fluid and lowers the sodium concentration.
This will most commonly result from hyperglycemia or infusion of mannitol. The circulating volume goes down due to increase in permeability of the vasculature or decrease in CO, activates ADH, leads to water retention.
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