Review Note
Last Update: 07/07/2024 02:01 AM
Current Deck: YelloW deck::Chapter_31:_Liver
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Normal liver tissue will take up sulfur colloid because it contains {{c1::Kupffer}} cells
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Kupffer cells are named after Karl Wilhelm von Kupffer, a Baltic German anatomist who discoverd the stellate macrophages. He was born in 1829 and died in 1902.
From radiopedia:
Sulfur colloid is taken up by the reticuloendothelial system, specifically the Kupffer cells which line the hepatic sinusoids. Because FNH is essentially focally malformed hepatic tissue, these lesions contain functioning Kupffer cells and take up technetium-99m sulfur colloid on nuclear imaging.
Classically, uptake pattern of Tc-99m sulfur colloid can be used to distinguish FNH from other liver lesions which do not contain normal liver cellularity, such as hepatic adenomas, HCC, and hepatic metastases. FNH is associated with normal or increased radiotracer uptake, whereas the others are associated with focal decreased uptake. Intense focal uptake is thought to be quite specific for FNH.
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