Review Note
Last Update: 07/22/2024 06:03 AM
Current Deck: - ALL SAR 1 ANKI Decks -::Medace Qbank
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Front (Question)
A 9-year-old girl presents for evaluation of regular vaginal bleeding.History reveals thelarche at age 7 and adrenarche at age 8. Which of the following is the most common cause of this condition in girls?
- Idiopathic
Gonadal tumors
McCune-Albright syndrome
Hypothyroidism
Tumors of the central nervous system
Back (Answer)
Idiopathic
Pubertal changes before the age of 8 years in girls and 9 years in boys are regarded as precocious. Although the most common type of precocious puberty in girls is idiopathic, it is essential to ensure close long-term follow-up of these patients to ascertain that there is no serious underlying pathology, such as tumors of the central nervous system or ovary. Only 1% to 2% of patients with precocious puberty have an estrogenproducing ovarian tumor as the causative factor. McCune-Albright syndrome (polyostotic fibrous dysplasia) is also relatively rare and consists of fibrous dysplasia and cystic degeneration of the long bones, sexual precocity, and café au lait spots on the skin. Hypothyroidism is a cause of precocious puberty in some children, making thyroid function tests mandatory in these cases. Tumors of the central nervous system as a cause of precocious puberty occur more commonly in boys than in girls; they are seen in about 11% of girls with precocious puberty.
Pubertal changes before the age of 8 years in girls and 9 years in boys are regarded as precocious. Although the most common type of precocious puberty in girls is idiopathic, it is essential to ensure close long-term follow-up of these patients to ascertain that there is no serious underlying pathology, such as tumors of the central nervous system or ovary. Only 1% to 2% of patients with precocious puberty have an estrogenproducing ovarian tumor as the causative factor. McCune-Albright syndrome (polyostotic fibrous dysplasia) is also relatively rare and consists of fibrous dysplasia and cystic degeneration of the long bones, sexual precocity, and café au lait spots on the skin. Hypothyroidism is a cause of precocious puberty in some children, making thyroid function tests mandatory in these cases. Tumors of the central nervous system as a cause of precocious puberty occur more commonly in boys than in girls; they are seen in about 11% of girls with precocious puberty.
Note (Extra)
Reference
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