Review Note

Last Update: 07/28/2024 09:22 PM

Current Deck: SK EBM Deck

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The following two trials showed the benefits of {{c1::finerenone::non-steroidal mineralocorticoid receptor antagonist}} in patients with CKD and T2DM:

  • {{c2::FIDELIO-CKD::2020 RCT}}: Patients w/ eGFR 25-60 w/ moderate proteinuria or eGFR 25-75 w/ severe proteinuria; primary outcome of renal failure, sustained decrease in eGFR, or death from renal causes
  • {{c3::FIGARO-CKD::2021 RCT}}: Patients with more mild CKD (eGFR up to 90 depending on proteinuria); primary outcome of death from CV causes, nonfatal MI or stroke, or hospitalization for HF
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ankihub_id
d7cfe9ec-3422-4093-919b-cf4b2b0e6279

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