Review Note

Last Update: 07/30/2024 08:27 AM

Current Deck: 01 Anki Avengers::LEAPMed 01::03BIO::BioChem 2T::BioChem 2T3S::4 Genetics Basis for Disease

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Ignoring the the binomial coefficient {N!/r!(N-r)!}, how is likelihood of data at RF (θ) computed if phase of informative parent is unknown?

Likelihood = {{c1::1/2 (θ^r x (1-θ)^(N-r)) + 1/2 (θ^r* x (1-θ)^(N*-r*))}}

Extra

1/2 (θ^r x (1-θ)^(N-r)) assuming all are nonrecombinant + 1/2 (θ^r x (1-θ)^(N-r)) assuming all are recombinant

example:
Where there are 3 offsprings

Likelihood ratio =

Lecture Notes

different in lecture

Missed Questions

Pathoma

Boards and Beyond

First Aid

Sketchy

Pixorize

Physeo

Additional Resources

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Biochemistry::#Thompson_8::10_Identifying_genetic_basis_for_human_disaease

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