Review Note
Last Update: 09/17/2024 02:51 PM
Current Deck: PACES::Conditions
PublishedCurrently Published Content
Text
Scleroderma Renal Crisis
Clinical features
{{c1::Sudden onset severe HTN
HTN retinopathy
HTN encephalopathy (headache, seizures)
AKI (with bland urinary sediment)
MAHA}}
Risk factors
{{c1::Diffuse skin involvement
Mod-high dose steroid use (≥15mg/day Pred)
Anti-RNAP3 (higher risk); Anti-centromere (lower risk)}}
Management
{{c1::Medical emergency
Effective and prompt BP control
Aim to lower BP to baseline within 72H
ACE-inhibitor +/- additional anti-HTNs}}
Clinical features
{{c1::Sudden onset severe HTN
HTN retinopathy
HTN encephalopathy (headache, seizures)
AKI (with bland urinary sediment)
MAHA}}
Risk factors
{{c1::Diffuse skin involvement
Mod-high dose steroid use (≥15mg/day Pred)
Anti-RNAP3 (higher risk); Anti-centromere (lower risk)}}
Management
{{c1::Medical emergency
Effective and prompt BP control
Aim to lower BP to baseline within 72H
ACE-inhibitor +/- additional anti-HTNs}}
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