Review Note
Last Update: 09/14/2024 07:23 PM
Current Deck: Joey Block 1::Joey Exam 2 (LO based deck)::Brennas Quiz 3::CBB 19: Cell Signaling 1
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Adenylate Cyclase:inactivation
Upon activation of Giα subunit in response to inhibitory hormone binding to receptor
•G{{c1::i}}α subunit migrates, interacts and inactivates the adenylyl cyclase.
• The inhibition of adenylyl cyclase causes {{c2::↓}} cAMP production
**Together: {{c3::↓}} production of cAMP → {{c4::↓}} activity of PKA → {{c5::↓}} phosphorylation of intracellular substrates and {{c5::↓}} signal**
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a298e5fb-35c6-4f27-8f1a-b670516e2048
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