Review Note
Last Update: 09/14/2024 07:23 PM
Current Deck: Joey Block 1::Joey Exam 2 (LO based deck)::Brennas Quiz 3::HOLD Q3::CBB25 enzyme inhibition
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Examples of drug enzyme-inhibitors include:
{{c1::oMethotrexate}}, used in cancer chemotherapy - inhibits DNA synthesis in malignant cells
o{{c2::Nucleoside analogue drug (AZT)}} - inhibits the DNA synthesis that is essential for the replication of retroviruses (HIV)
o{{c3::β-lactam}} antibiotics - (penicillin and amoxicillin, act by inhibiting enzymes involved in bacterial cell wall synthesis.
o{{c4::Enalapril}}, {{c4::Lisinopril}}, and {{c4::captopril}}- drugs used to lower blood pressure by blocking the enzyme that cleaves angiotensin I to form angiotensin II (a potent vasoconstrictor )
o{{c5::Aspirin}}, a NSAID, irreversibly inhibits COX, the enzyme that catalyzes the synthesis of prostaglandin and thromboxane synthesis
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