Review Note
Last Update: 09/30/2024 05:34 PM
Current Deck: Geneeskunde::3e bachelor::long & hart::ZSO 4 hemodynamiek
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Question
In
an organ perfused at a constant pressure, blood flow is altered by
internal physical forces that change vessel radius by activation or
deactivation of smooth muscle contraction. Changes in vessel radius can
also be produced by changes in external physical forces on blood
vessels. What combination of external and internal physical forces would
cause the greatest restriction of blood flow in the skeletal muscle
circulation?
Title
QType (0=kprim,1=mc,2=sc)
2
Q_1
An increase in interstitial pressure and an increase in arteriolar smooth muscle contraction
Q_2
A decrease in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_3
An increase in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_4
An decrease in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_5
HAHAHAHAHA
Answers
1 0 0 0 0
Sources
The point
Extra 1
Rationale: At
constant pressure, blood flow through an organ is dependent on total
vascular resistance in the organ. Resistance of the arterioles
contributes by far the most to total vascular resistance in an organ, so
changes in their diameters have a profound effect on blood flow through
the organ when arterial pressure is not changed. Contracting arterial
smooth muscle in arteries to an organ reduces blood flow to an organ.
Increasing pressure on the outside of arterioles tends to compress them,
thereby increasing their resistance to flow. This can occur from edema
in the organ from external compressive forces from the organ itself,
such as muscle contraction. A reduction in arteriolar constriction and
external compression in the muscle would cause a marked increase in
muscle blood flow. There is no way to predict what restriction of blood
flow may occur in an organ when the two variables in this example change
in opposite directions. Blood flow there will be affected by the
relative contribution of each, which could cancel one another out or
result in an increase in blood flow.
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