Review Note

Last Update: 09/30/2024 05:34 PM

Current Deck: Geneeskunde::3e bachelor::long & hart::ZSO 4 hemodynamiek

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Question
In an organ perfused at a constant pressure, blood flow is altered by internal physical forces that change vessel radius by activation or deactivation of smooth muscle contraction. Changes in vessel radius can also be produced by changes in external physical forces on blood vessels. What combination of external and internal physical forces would cause the greatest restriction of blood flow in the skeletal muscle circulation?
Title
QType (0=kprim,1=mc,2=sc)
2
Q_1
An increase in interstitial pressure and an increase in arteriolar smooth muscle contraction
Q_2
A decrease in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_3
An increase in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_4
An decrease in interstitial pressure and a decrease in arteriolar smooth muscle contraction
Q_5
HAHAHAHAHA
Answers
1 0 0 0 0
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The point
Extra 1
Rationale: At constant pressure, blood flow through an organ is dependent on total vascular resistance in the organ. Resistance of the arterioles contributes by far the most to total vascular resistance in an organ, so changes in their diameters have a profound effect on blood flow through the organ when arterial pressure is not changed. Contracting arterial smooth muscle in arteries to an organ reduces blood flow to an organ. Increasing pressure on the outside of arterioles tends to compress them, thereby increasing their resistance to flow. This can occur from edema in the organ from external compressive forces from the organ itself, such as muscle contraction. A reduction in arteriolar constriction and external compression in the muscle would cause a marked increase in muscle blood flow. There is no way to predict what restriction of blood flow may occur in an organ when the two variables in this example change in opposite directions. Blood flow there will be affected by the relative contribution of each, which could cancel one another out or result in an increase in blood flow.

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