Review Note
Last Update: 10/09/2024 02:42 PM
Current Deck: Pharmacology 2::Thrombosis & Haemostasis
PublishedCurrently Published Content
Front
Name disadvantages of Xabans
Back
Xabans are selective for the inhibition of Xa
- Big disadvantages: heavy bleeding
- Interactions w/ strong CYP3A4 + P-gp inhibitors —> bleeding
- Interaction w/ strong CYP3A4 + P-gp inductors —> thrombosis
CYP3A4: enzyme that metabolises drugs in the liver
P-gp: transporter which influences distribution and bioav. of drugs
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