Review Note
Last Update: 10/09/2024 04:34 PM
Current Deck: FOM_B2
Published
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Front
In rheumatic heart disease, which immune mechanism contributes most to the cardiac damage observed?
A) Direct bacterial invasion of heart tissue
B) Autoimmune cross-reactivity with cardiac myosin
C) Release of bacterial endotoxins
D) Viral co-infection with Streptococcus
Back
B) Autoimmune cross-reactivity with cardiac myosin
Rationale: Rheumatic fever involves molecular mimicry, where antibodies produced against streptococcal M-protein also attack cardiac myosin, leading to cardiac inflammation and damage
Rationale: Rheumatic fever involves molecular mimicry, where antibodies produced against streptococcal M-protein also attack cardiac myosin, leading to cardiac inflammation and damage
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