Review Note
Last Update: 10/09/2024 07:25 PM
Current Deck: 001 Eddies M2 Lecture Decks::4A Renal::2 Tubular Transport
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Glucose is reabsorbed at PCT through 2 co-transpoters
⇒ {{c1::SGLT1}} ⇒ {{c2::high::high/low}} affinity, {{c2::low::high/low}} capacity
⇒ {{c1::SGLT2}} ⇒ {{c2::low::high/low}} affinity, {{c2::high::high/low}} capacity
***theres a LIMIT to the amount of glucose kidney can re-absorb called {{c3::Transport Maximum (Tm)}}
⇒ {{c3::Tm}} occurs at plasma glucose ~{{c4::300}} mg/dL
⇒ {{c1::SGLT1}} ⇒ {{c2::high::high/low}} affinity, {{c2::low::high/low}} capacity
⇒ {{c1::SGLT2}} ⇒ {{c2::low::high/low}} affinity, {{c2::high::high/low}} capacity
***theres a LIMIT to the amount of glucose kidney can re-absorb called {{c3::Transport Maximum (Tm)}}
⇒ {{c3::Tm}} occurs at plasma glucose ~{{c4::300}} mg/dL
Extra
**SGLT2 inhibitors are the drug we use
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