Review Note

Last Update: 10/21/2024 09:21 AM

Current Deck: BUMed Mother Deck::YL2.S1-PATHOLOGY::PTH.S1.L07.RBC & Bleeding Disorders (no edit)::IV - Anemia of Diminished Erythropoiesis

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Front

Multipotent myeloid stem cells are suppressed, leading to bone marrow failure and pancytopenia

Back
Aplastic anemiaEtiology:→ Extrinsic, immune-mediated suppression of bone marrow progenitors→ Intrinsic abnormality of stem cells BUT 65% idiopathic

Treatment: HSC transplantation (non-transfused patients) with immunosuppressive radiation or chemotherapy

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