Review Note

Last Update: 10/21/2024 09:21 AM

Current Deck: BUMed Mother Deck::YL2.S1-PATHOLOGY::PTH.S1.L09.Hemodynamic Disorders, Thromboembolic Disease, and Shock

Published

Fields:

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{{c1::Platelet adhesion::Platelet Function?}}
  • Mediated largely via interactions between the platelet surface receptor glycoprotein Ib (Gplb) and vWF in the subendothelial matrix
  • Deficiency of Gplb → {{c1::Bernard-Soulier syndrome}}
Back Extra

  • Platelets rapidly change shape following adhesion
  • Accompanied by conformational changes in cell surface (particularly phosphatidylserine) to the platelet surface

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