Review Note
Last Update: 10/21/2024 09:21 AM
Current Deck: BUMed Mother Deck::YL2.S1-PATHOLOGY::PTH.S1.L09.Hemodynamic Disorders, Thromboembolic Disease, and Shock
Published
Fields:
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{{c1::Platelet adhesion::Platelet Function?}}
- Mediated largely via interactions between the platelet surface receptor glycoprotein Ib (Gplb) and vWF in the subendothelial matrix
- Deficiency of Gplb → {{c1::Bernard-Soulier syndrome}}
Back Extra
- Platelets rapidly change shape following adhesion
- Accompanied by conformational changes in cell surface (particularly phosphatidylserine) to the platelet surface
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