Review Note

Last Update: 10/21/2024 10:30 AM

Current Deck: BUMed Mother Deck::YL2.S1-PATHOLOGY::PTH.S1.L11.Bones, Joints, and Soft Tissue Tumors

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{{c1::Calcium pyrophosphate crystal deposition disease (pseudogout)}}
  • Usually occurs in individuals > 50 years of age
  • Divided into sporadic (idiopathic), hereditary, and secondary types
  • An autosomal dominant variant is caused by germline gain-of-function mutations in ANKH, an inorganic pyrophosphate transporter, that result in crystal deposition and osteoarthritis
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