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Last Update: 01/24/2025 08:27 AM

Current Deck: Geneeskunde::3e bachelor::Nier en spijs::ZSO 32: Nierfarmacologie::Shanna's Snelweg naar Succes

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Commit #268356

Which one of the following is characteristic of nifedipine treatment in patients with essential hypertension?

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Commit #268356

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(A) Competitively blocks angiotensin II at its receptor

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(B) Decreases calcium efflux from skeletal muscle

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Commit #268356

(D) Decreases calcium influx into smooth muscle

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Commit #268356

(E) Increases calcium excretion in the urine

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Commit #268356

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Commit #268356

Nifedipine is a prototype L-type calcium channel blocker and lowers blood pressure by reducing calcium influx into vascu lar smooth muscle. It has no effect on angiotensin~converting enzyme. Calcium efflux from skeletal muscle cells does not involve the L-type ca2+ channel. The plasma renin level may inert:ase as a result of the compensatory response to reduced blood pressure. Calcium channel blockers have negligible effects on urine calcium. The answer is D.