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Last Update: 01/24/2025 08:27 AM
Current Deck: Geneeskunde::3e bachelor::Nier en spijs::ZSO 32: Nierfarmacologie::Shanna's Snelweg naar Succes
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Question
Commit #268356
A significant number of patients started on ACE inhibitor
therapy for hypertension are intolerant and must be switched
to a different class of drug. What is the most common mani
festation of this intolerance?
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Commit #268356
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Commit #268356
(A) Angioedema
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(B) Glaucoma
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(C) Headache
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(D) Incessant cough
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Commit #268356
(E) Ventricular arrhythmias
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Commit #268356
Katzung
Extra 1
Commit #268356
Chronic, intolerable cough is an important adverse effect of
captopril and other ACE inhibitors. It may be associated with
increased bradykinin levels because ARBs are not as frequently associated with cough. The ACE inhibitors are very com
monly used in hypertensive diabetic patients because of their
proven benefits in reducing diabetic renal damage. The ACE
inhibitors are not associated with glaucoma; angioedema is
not as common as cough; and headache and arrhythmias are
rare. The answer is D.