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Last Update: 01/24/2025 08:27 AM
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Question
Commit #268356
A 45-year-old man is brought to the emergency department
with mental obtundation. He is found to have a blood pres
sure of220/160 mm Hg and retinal hemorrhages. Which one
of the following is used in severe hypertensive emergencies, is
short-acting, acts on a G-protein-coupled receptor, and must
be given by intravenous infusion?
QType (0=kprim,1=mc,2=sc)
Commit #268356
2
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Commit #268356
(A) Aliskiren
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(B) Captopril
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(C) Fenoldopam
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(D) Hydralazine
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(E) Losartan
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Commit #268356
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Extra 1
Commit #268356
Fenoldopam, nitroprusside, and propranolol are the drugs
in the list that have been used in hypertensive emergencies.
Fenoldopam and nitroprusside are used by infusion only, but
nitroprusside releases nitric oxide, which acts on intracellular
guanylyl cyclase. The answer is C.