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Last Update: 01/24/2025 08:27 AM
Current Deck: Geneeskunde::3e bachelor::Nier en spijs::ZSO 32: Nierfarmacologie::Shanna's Snelweg naar Succes
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Question
Commit #268356
An 18-month-old boy dies from an accidental overdose of
acetaminophen. Which of the following is the most likely
cause of this patient's death?
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(A) Arrhythmia
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(B) Hemorrhagic stroke
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(C) Liver failure
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(D) Noncardiogenic pulmonary edema
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(E) Respiratory failure
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Commit #268356
In overdose, acetaminophen causes fulminant liver failure as a result of its conversion by hepatic cytochrome P450 enzymes to a highly reactive metabolite (see also Chapter 4, Figure 4-1). The answer is C.