Review Note

Last Update: 02/05/2025 08:20 AM

Current Deck: BPT QC

Published

Currently Published Content

Front

You are asked to review a middle-aged gentleman who has recently been gaining weight despite being on maximal biguanide and sulphonylurea for his Type 2 Diabetes Mellitus. His HbA1C is 8.6% and his BMI is 36. Addition of which of the following would be of greatest help in both reducing his weight and improving control of BSL?

A. Acarbose

B. Pioglitazone

C. Insulin glargine

D. Exenatide

E. Sitagliptin

Back

D. Exenatide - GLP1 analogue, increases insulin, increases satiety, reduced gastric emptying = improved BSL and weight loss

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A. Acarbose - not associated with weight loss

B. Pioglitazone (thiazolidinedione) - associated with weight gain, fluid retention, and increased risk of heart failure.

C. Insulin glargine - associated with weight gain

E. Sitagliptin (DPP4 inhibitor) - typically weight neutral

Current Tags:

#Endocrinology #POWH #T2DM

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