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Notes in
Protein and Lipid Metabolism Lecture
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09/14/2023
The last bond (between beta and gamma phosphates) on ATP has the {{c1::greatest energy}} and is used for {{c1::muscle contractions }}The second b…
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09/14/2023
how protein Ends up in different compartments{{c1::Proteins to be secreted}} = carbohydrate side chain on serine / threonine residues within spec…
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09/14/2023
How proteins end up in different compartments:{{c1::TO lysosome =}} more sugars added to protein {{c1::TO cell membrane vesicle =}} ter…
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09/15/2023
{{c1::Prion disease}} = mad cow disease (alpha helix ⇒ beta sheet aggregation in brain){{c1::Cystic Fibrosis}} = deficient Cl- channels so n…
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09/15/2023
{{c1::Alpha-Antitrypsin disease}} = A1AT protein misfolding leads: 1. {{c2::Polymerization}} and cirrhosis of liver (gain of toxic func…
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09/15/2023
Tetanus toxin: Toxin is a {{c1::protease}} that cleaves receptors. So NO release of {{c1::inhibitory NT }
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09/15/2023
Botulinum Toxin: {{c1::Inhibits}} release of Ach by exocytosis (paralysis)
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09/15/2023
Urea cycel disorder = diet low in {{c1::AA}}
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09/15/2023
Treatments for Urea cycle disorders: {{c2::1. Sodium phenylbutyrate}} (metabolized into phenylacetate) = {{c1::conjugates with glutamin…
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09/15/2023
Insulin binds to RTK receptors and causes two pathways:1. {{c1::Ras 1/MAPk pathway}}⇒ cell growth (insulin acts as glycogen synthesis and lipogenesis)…
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