Notes in HIV: Clinical Presentation & Opportunistic Infections

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Published 01/07/2024 HIV natural progression - order of infections {{c1::}}
Published 01/07/2024 Understand the role of CD4+T cell count and viral load in assessing and monitoring diseaseCD4 cells {{c1::T helper cells → lose function and popu…
Published 01/07/2024 Signs and symptoms of primary HIV infection {{c1::80-90% fever Sore throat Cervical lymphadenopathy 40% non specific maculopapular…
Published 01/07/2024 HIV opportunistic infectionsRespiratory - acute cough and feverBacterial pneumonia CAP {{c1::S pneumoniae and H influenza }}Influenza a…
Published 01/07/2024 HIV opportunistic infections Respiratory - acute cough and feverMycobacterium {{c1::TB !!!}} (up to 10% of adults with HIV and acute co…
Published 01/07/2024 HIV opportunistic infections Respiratory - acute cough and feverFungal Pneumocystis jirovercii pneumonia (PJP)Spread - {{c1::person to …
Published 01/07/2024 HIV opportunistic infections Respiratory - chronic cough and fever Mycobacterium {{c1::Pulmonary TB !!!}}Bacterial {{c1::Recurrent…
Published 01/07/2024 HIV opportunistic infections Respiratory prophylactic management CD4 <200 {{c1::Co trimoxazole for PJP and Toxoplasmosis }}CD4 …
Published 01/07/2024 HIV opportunistic infections GIT{{c2::Oral hairy leukoplakia }}Caused by {{c1::EBV}}, much less common now with active antiretroviral therap…
Published 01/07/2024 HIV opportunistic infections GITAcute GI{{c1::Salmonella and shigella}}Chronic diarrhea and wasting 35% parasitic ({{c1::cryptosporidium, gi…
Published 01/07/2024 HIV opportunistic infections Skin Scabies Groin and web spaces of fingers Treat - {{c1::topical benzyl benzoate and repeat&nb…
Published 01/07/2024 HIV opportunistic infections Skin  Viral - with increased freq and severity{{c1::Herpes zoster aka shingles (treat - acyclovir)Genital …
Published 01/07/2024 HIV opportunistic infections Malignancy Kaposi sarcoma Due to{{c1::HHV8 }}Multifocal neoplasm of {{c2::lymphatic endothelium deriv…
Published 01/07/2024 HIV opportunistic infections Eye disease {{c1::HIV microangiopathy }}Multiple retinal microaneurysms +/- hemmorhages Opportunistic…
Published 01/07/2024 HIV opportunistic infections CNS Toxoplasma gondii (parasite)Epi - warm blooded animals (cats/birds) and transmitted through oral ingestion&…
Published 01/07/2024 HIV opportunistic infections CNS Primary CNS lymphoma CD4<{{c1::50}}
Published 01/07/2024 HIV opportunistic infectionsCNS Viral {{c1::Progressive multifocal leukoencephalopathy (PML)}} due to {{c2::JC virus }}JC vir…
Published 01/07/2024 HIV opportunistic infections CNS Meningitis {{c1::Cryptococcus }}Prolonged fever and meningism Investigations - {{c2::hi…
Published 01/07/2024 HIV associated infectionsCNS {{c1::HIV associated dementia }}Stage correlates with CSF HIV viral RNA Infection of brain {{c2::macrophag…
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