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Notes in
5. Bipolar disorders
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Published
06/26/2023
Bipolar I → DSM-5 Criteria for diagnosis, it is necessary to meet criteria for {{c1::manic episodes}}manic episodes may have been preceded/f…
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06/26/2023
Bipolar I → DSM-5 Cont'd manic episode a distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormall…
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06/26/2023
bipolar I → DSM-5 cont'd hypomanic episode a distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnor…
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06/26/2023
Bipolar I → DSM-5 cont'd Major Depressive Disorder {{c1::five or more}} of the follwoing that have been present during the {{c1::same 2…
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important facts he said must rule out {{c1::bipolar}} before mddmajor receptor associated with bipolar → {{c1::dopamine}}
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before ever giving an antidepressant → must rule out {{c1::bipolar}}serotonin has downstream effect on dopamine, it increases it and can cause an…
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06/26/2023
in order to diagnose Bipolar, must have had {{c1::one manic}} episode at any time in their life
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Mania vs hypomania hypomania is less severe of mania. they both have changes in mood, energy, activity, behavior, sleep, and congition, but with …
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06/26/2023
Screening for mania → DIG FAST D → {{c1::distractibility}}I → {{c1::Indiscretion}}G → {{c1::Grandiosity}}F → {{c2::flight of …
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Bipolar I → epidemiology and comorbidities lifetime prevalence is lower than MDD manic episodes more common in {{c1::men}} → depressive…
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06/26/2023
Bipolar I → clinical features patients MUST have had a {{c1::manic disorder for diagnosis}}if currently depressed, cannot be distinguished f…
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06/26/2023
Bipolar I → treatment overview hospitalization if warranted. Acute {{c1::mania}} may warrant admission. Hospitalization is difficult for man…
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06/26/2023
Bipolar I → treatment of acute mania drugs (3) → {{c1::lithium, valporate, carbamazepine/oxcarbazepine}} mneumonic → {{c2::"Val-poorly Lit t…
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06/26/2023
Bipolar I → treatment of acute depression/maintenance difficult because can be unresponsive to typical antidepressants or antidepressants → …
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06/26/2023
bipolar treatment → adverse effects Risperidone → can cause increased {{c1::prolactin}}, weight gain, EPS Lithium → "narrow therapeutic…
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06/26/2023
Extrapyramidal side effects (EPS), commonly referred to as {{c1::drug-induced movement disorders}} are among the most common adverse dr…
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PA-C really likes {{c1::partial agonists}} for treatment
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Bipolar I → prognosis if pt has single manic episode → 90% will likely have another as disorder progresses, time between episodes decreases …
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06/26/2023
Bipolar II → DSM-5 criteria for a diagnosis of bipolar II, must have criteria for current or past {{c1::hypomanic episode}} AND a current or…
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06/26/2023
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comparison
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06/26/2023
bipolar II overview and clinical features lifetime prevalence of 0.3-4.8% has clinical features of {{c1::MDD}} combined w/ those o…
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06/26/2023
random fun fact → number one disability in the world → {{c1::depression}} → kills brain cells
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06/26/2023
suggestive of bipolar diagnosis early age onset {{c1::psychotic depression}} before 25 yorapid onset and offset of depression episodes (<…
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cyclothymic disorder → DSM-5 criteria for at least {{c1::2 years}} → 1 year in children and adolescents there have been numerous periods w/&…
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06/26/2023
cyclothymia → overview symptomatically {{c1::mild form of bipolar II}}described as chronic {{c1::fluctuating mood disturbance}}it is di…
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06/26/2023
cyclothymia → epidemiology and etiology epidemiology and comorbidities 3-5% of all psychiatric outpts. Overall, 1% prevalence typically…
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06/26/2023
cyclothymia → treatment and prognosis treatment first line → {{c1::mood stabilizers and antimanic medications}}caution when treating de…
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06/26/2023
PMDD → DSM-5 criteria in the majority of menstrual cycles, at least {{c1::five symptoms}} must be present in the {{c1::final week befor…
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06/26/2023
PMDD: DSM-5 cont'd in addition, {{c1::one or more}} of the following symptoms must be present, to total of {{c1::five symptoms}} when c…
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06/26/2023
PMDD overview somatopsychic illness triggered by changing levels of {{c1::sex steroids}} that accompany an ovulatory menstrual cycle. it occ…
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06/26/2023
PMDD → treatment symptomatic treatment analgesics for pain sedatives for anxiety/insomnia diuretics for edema some pts may re…
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