Notes in Pharmacology 2::Thrombosis & Haemostasis

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Status	Last Update	Fields
Published	10/09/2024	Differentiate b/w arterial & venous thrombosis
Published	10/09/2024	A t{{c1::hrombus}} gets dissolved via {{c2::fibrinolysis}} activated by plasmin and degraded into {{c3::D-Dimers}} (excreted by renal system)
Published	10/09/2024	Name the available pharmacological interventions in thrombosis (4 classifications of drugs)
Published	10/09/2024	{{c1::Anticoagulants}} interfere with the formation of blood clots and the termination of clot formation
Published	10/09/2024	{{c1:: Antiplatelets}} interfere with the {{c2::formation of platelet plugs}} (stage one of bleeding control)
Published	10/09/2024	Name anticoagulatants and the aim of them (3+1)
Published	10/09/2024	What is the most common complication of anticoagulants?
Published	10/09/2024	Describe the mechanism of action of heparin, pros and cons
Published	10/09/2024	Describe mechanism of action, pros and cons of LMWH
Published	10/09/2024	Describe mechanism of action, pros and cons of Vit. K antagonists
Published	10/09/2024	Describe mechanism of action, pros and cons of plasminigen activators
Published	10/09/2024	Describe mechanism of action of antiplatelets (4)
Published	10/09/2024	Name the most common disadvantage of antiplatelets
Published	10/09/2024	Direct factor Xa inhibitors block the enzyme called {{c1::factor Xa}}, preventing the conversion of {{c2::prothrombin}} to {{c2::t…
Published	10/09/2024	Benefits of Xabans over Warfarin or other anticoagulats
Published	10/09/2024	Name disadvantages of Xabans
Published	10/09/2024	Define antidotes
Published	10/09/2024	{{c1::Protamine Sulfate}} is the antidote for anticoagulant {{c2::Heparin}}. {{c1::Vitamin K}} is the antidote for anticoagulant {{c2::Warfarin}}…
Published	10/09/2024	{{c1::Andexanet alpha}} neutralises {{c2::direct factor Xabans}} (Xa inhibitors). {{c1::Transexamic acid}} neutralises {{c2::fibronolytics}} (MoA…
Published	10/09/2024	Which of the following are correct about Aspirin: inhibits coagulation cascadeinhibits platelet activationinhibits production of thromboxane A2in…
Published	10/09/2024	Do ADP receptor antagonists inhibit fibrinolytic cascade?
Published	10/09/2024	Can ADP receptor antagonists be safely combined with proton pump inhibitors?
Published	10/09/2024	Can Clopidogrel be taken with Pantaprazole?
Published	10/09/2024	{{c2::Heparins}} bind directly to {{c1::antithrombin}} and can be neutralised by {{c3::protamin}}
Published	10/09/2024	True or False Coumarines are largely matabolised by CYP2C9 and CYP3A4 in the liver
Published	10/09/2024	True or False Coumarines are effective within 24 hrs after administration
Published	10/09/2024	True or False Coumarines inhibit carboxylation of factors II, IX, X in liver
Published	10/09/2024	True or False Direct oral anticoagulants inhibit carboxylation of factors II, VII, IX, X in liver
Published	10/09/2024	True or False Direct oral anticoagulants are effective within 24 hrs after administration
Published	10/09/2024	True or False Direct oral anticoagulants can safely be combined with antimycotics and HIV protease inhibitors
Published	10/09/2024	True or False Direct oral anticoagulants are selective factor Xa or factor IIa inhibitors
Published	10/09/2024	True or False Fibrinolytics inhibit the prod. of tissue factor pathway inhibitor
Published	10/09/2024	True or False Fibrinolytics inhibit the prod. of tissue plasminogen activator
Published	10/09/2024	True or False Fibrinolytics have fibrin-specificity to diminish the risk of systemic lytic state
Status	Last Update	Fields