Notes in Cardio Hemodynamics & Parameters

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Published 09/20/2023 {{c1::Shock}} is circulatory failure of the whole body.... blood flow to tissues is dangerously low → cellular injury → multiple organ failu…
Published 09/20/2023 clinical testing in cardiology- consider symptoms and risk factors (age, congenital, family hyistory, blood pressure)  - assess acuity, severity …
Published 09/19/2023 cardiac output (CO) = {{c1::stroke volume (SV)}} X {{c1::heart rate (HR) }} blood pressure (BP) equation: MAP – {{c3::CVP}} = CO x {{c4::SVR}}*an…
Published 09/19/2023 {{c1::arteries}} carry blood away from the heart*{{c8::higher::higher/lower}} pressure, low {{c3::compliance}}{{c2::veins}} carry blood toward heart*{…
Published 09/19/2023 pipes and pumps{{c2::ejection fraction (EF)}} = {{c1::SV}} / {{c3::LVEDV}}{{c3::LVEDV}} - LVESV = {{c1::SV}}
Published 09/19/2023 veins are low {{c1::pressure}}*{{c4::manual pressure}} is enough for hemostasis arteries are high {{c1::pressure}}*endothelial {{c5::factors}} → vasoc…
Published 09/19/2023 the neurotransmitter released by the preganglionic neurons of both the sympathetic and parasympathetic nervous system is {{c1::acetylcholine}} 
Published 09/20/2023 sympathetic nervous system- preganglionic neurons are called {{c5::cholinergic}} bc they secrete {{c5::ACh}} → bind to {{c7::nicotinic}} receptors on …
Published 09/20/2023 parasympathetic nervous system- both preganglionic and postganglionic neurons of parasympathetic are called cholinergic because th…
Published 09/19/2023 {{c1::electrocardiogram (EKG)}} focuses on heart's electrical activity, as a measure of how organ is functioning{{c2::echocardiography (echo)}} is a f…
Published 09/20/2023 age vs heart conditionsyounger (25 yo) → {{c1::Hypertrophic Cardiomyopathy (HCM)}}→ lower risk → prior symptoms→ family history → tests: EKG…
Published 09/19/2023 after sustaining a cut ...→ {{c1::intima}} layer carries factors that promotes vasoconstriction and platelet plugging → {{c1::media}} layer assis…
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Published 09/19/2023 α-receptors in sympathetic system α-1 maintains {{c2::blood pressure}} α-2 works as {{c3::negative feedback loop}} *receptors are on {{c1::presy…
Published 09/19/2023 β-receptors in sympathetic systemβ-1- mainly located in heart → increased {{c2::HR}} and {{c2::contractility}} - present in kidneys → increased {…
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Published 09/21/2023 pharmacological regulation of sympathetic nervous systemdirect agonists: - α-{{c2::1::#}} agonist → vasoconstriction, increased BP, pupil dilation-&nb…
Published 09/19/2023 most 1st generation beta blockers are {{c1::non-selective::selective/non-selective}}
Published 09/19/2023 pharmacological regulation of parasympathetic nervous systemdirect cholinomimetic: mimics {{c1::acetylcholine}}    indirect cholinomim…
Published 09/20/2023 increased parasympathetic ({{c10::ACh::which NT?}}-driven muscarinic) activity results in "DUMB HAVES"D{{c1::efecation}} U{{c2::rination}} M{{c3::uscl…
Published 09/20/2023 organophosphate poisoning → {{c1::acetylcholinesterase}} inhibition → acute cholinergic toxicity → parasympethatic system is over activatedt…
Published 09/21/2023 target receptor of medication used to treat asthma exacerbation is {{c1::β-2}}*ex: {{c4::albuterol}} is a {{c1::β-2}} agonist→ drugs given to tre…
Published 09/20/2023 vasovagal syncope (VSS)- abrupt/prolonged standing → blood pools in lower extremities and decreased {{c1::venous return}} → brain thinks hypovolemia →…
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Published 09/19/2023 Types of shock1. {{c1::hypovolemic}}: shock induced by low fluid volume of blood2. {{c2::cardiogenic}}: shock induced by damage to/malfunction of hear…
Published 09/20/2023 Hypovolemic shock- shock induced by {{c1::low fluid volume}} of blood - can be {{c2::hemorrhagic}} (ruptured blood vessels) or non-hemorrhagic (n…
Published 09/19/2023 Cardiogenic shock- shock induced by damage to/malfunction of {{c1::heart}}... “pump failure” - heart attack → muscle cell death → weaker contractions…
Published 09/19/2023 Obstructive shock- physical constriction of muscle → weaker {{c4::contraction}} → decreased BP*cardiac {{c3::tamponade}}*pericardiocentesis …
Published 09/19/2023 Distributive shock- {{c2::anaphylactic}} shock: allergic reaction → histamine release → vasodilation of blood vessels → leaky blood vessels → low BP -…
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Published 09/19/2023 oxygen delivery relies on maintenance of blood {{c1::volume}}
Published 09/19/2023 Primary hemostasis- {{c1::endothelial injury}} → {{c4::exposure}} → {{c6::adhesion}} → {{c8::activation}} → {{c11::aggregation}} 1) {{c1::endothelial…
Published 09/19/2023 primary hemostasis and secondary hemostasis (aka coagulation):
Published 09/19/2023 {{c1::vWF::factor}} is involved in both primary and secondary hemostasis 
Published 10/05/2023 secondary hemostasis*overall: clotting factors sequentially proteolytically activated → activation of fibrin (factor {{c1::Ia::#}}) → forms mesh …
Published 09/20/2023 Factor IIa ({{c7::thrombin}}) facts- IIa uses {{c1::Ca2+}} ions as cofactor- IIa activates {{c2::platelets}}- IIa activates 3 cofactors ({{c3::V}}, {{…
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Published 10/05/2023 Clot regulation- anticoagulation happens {{c1::during::during/after}} primary and secondary hemostasis and regulates clot formation - {{c7::clot retra…
Published 10/05/2023 fibrinolysis = gradual degradation of {{c1::fibrin}} mesh- starts {{c2::2}} days after hemostasis occurs - {{c4::tissue plasminogen activator (tP…
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Published 10/05/2023 warfarin - inhibits {{c1::epoxide reductase::enzyme}} activity → prevents vitamin {{c2::K}} from being recycled → cannot continue creating certia…
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Published 10/05/2023 rivarox{{c1::aban}}, apix{{c1::aban}}, edox{{c1::aban}} inhibit factor Xa
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