Notes in Pharm 241

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Published 02/12/2024 EXCLUSIONS FOR SELF-CARE – Ophthalmic Disorders• {{c1::Eye}} pain• {{c1::Blurred}} vision, not associated with ocular ointments•&n…
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Relieve of irritation symptoms• Prevent corneal and non-corneal tissue damageGeneral Approach• No…
Published 02/12/2024 NON-PHARMACOLOGICAL THERAPY – Dry Eyes• {{c1::Warm}} compresses• Good eyelid {{c1::hygiene}}• {{c1::Humidifiers}}• Avoidance of {{c2::dry, dusty place…
Published 02/12/2024 **Ophthalmic Lubricants{{c1::Artificial tear products}}: varying degrees of viscosity based on ingredients• Low viscosity: {{c1::mild dry eyes}}• High…
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Published 02/12/2024 Non-medicated Ointments• Main ingredients: {{c1::white petrolatum and mineral oil}}• {{c1::Long}} retention time in eye• {{c1::Twice daily}} dosing, a…
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Remove or avoid allergen or irritant• Limit or reduce allergic reaction severity• Alleviate or im…
Published 02/12/2024 NON-PHARMACOLOGICAL THERAPY – Allergic Conjunctivitis• Remove or avoid {{c1::allergens (pollen, dust mites, pet dander, topical eye products)}}• {{c1:…
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Published 02/12/2024 Product Selection - Allergic Conjunctivitis1. {{c1::Artificial tear products}}: first line2. {{c1::Antihistamine/decongestant}} (pheniramine/naphazoli…
Published 02/12/2024 Self-care of otic disorders limited to extenral auditory canal (EAC)1. {{c1::Excessive or impacted cerumen}}2. {{c1::Water clogged ear}}**Children hav…
Published 02/12/2024 EXCLUSIONS FOR SELF-CARE – Otic Disorders• Signs of {{c1::infection}}• Pain related to {{c1::ear discharge}}• {{c1::Bleeding or signs}}&nbsp…
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACHTreatment Goals• Safely remove cerumen• Prevent harm to the EACGeneral Approach• Non-pharmacological therapy• Phar…
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Published 02/12/2024 **Carbamide peroxide 6.5%**• Carbamide peroxide 6.5% in {{c1::anhydrous glycerin}}: only FDA-approved {{c1::for removal of impacted cerumen …
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACH (Water Clogged Ears)Treatment Goals• Rule out exclusion criteria for self- care• Safe and effective agents to pre…
Published 02/12/2024 NON-PHARMACOLOGICAL THERAPY – Water Clogged Ears{{c1::Ear plugs or caps for swimming}}• ClearEars, AquaEars, Bioears• Insert in EAC x 5 to 10 minutes …
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Published 02/12/2024 EXCLUSIONS FOR SELF-CARE – Orofacial Pain/Discomfort{{c1::CANKER SORES}}• Lesions {{c2::≥14 days}}• Frequently recurring {{c2::lesions}}• Systemic {{c…
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACH (Canker Sores)Treatment Goals• Relief of symptoms of pain and irritation, to resume daily functions• Prevent seco…
Published 02/12/2024 NON-PHARMACOLOGICAL THERAPY - Sores• {{c1::Nutritional supplements, if deficiency• Elimination of food or allergen• Stress removal and relaxation…
Published 02/12/2024 **PHARMACOTHERAPY – Oral Debriding and Wound Cleansing Agents• {{c1::Carbamide peroxide 10%, hydrogen peroxide 1.5%}}• Release oxygen on contact to re…
Published 02/12/2024 PHARMACOTHERAPY – Canker Sores• {{c3::Topical oral anesthetics}}: {{c1::indicated for temporary relief of pain}} associatedwith RAS (e.g. {{c1::benzoc…
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Published 02/12/2024 How are cold sores transmitted?- {{c1::direct contact (kissing, sharing utensils)- infection thru break in mucous membranes --> latent --> react…
Published 02/12/2024 TREATMENT GOALS and GENERAL APPROACH (cold sores)Treatment Goals• Relief of symptoms of pain and irritation, while lesions heal• Prevent secondary com…
Published 02/12/2024 NON-PHARMACOLOGICAL THERAPY – Cold Sores• {{c1::Clean lesions by washing with mild soap solutions• Handwashing• Keep skin area moist to prevent c…
Published 02/12/2024 PHARMACOTHERAPY – Cold Sores• {{c1::Docosanol 10% (Abreva cream)}} ≠ {{c1::Abreva Conceal (nonmedicated patch)}}• {{c2::Abreva (docosan…
Published 02/12/2024 BACKGROUND & DEFINITIONS - Heartburn and DyspepsiaHeartburn (pyrosis): {{c1::burning sensation in stomach or lower chest, risingtoward the ne…
Published 02/12/2024 CLINICAL PRESENTATION – Heartburn and Dyspepsia• Heartburn: {{c1::burning sensation in stomach or lower chest, rising toward the neck and sometim…
Published 02/12/2024 EXCLUSIONS FOR SELF-CARE – Heartburn and Dyspepsia• Frequent {{c1::heartburn}}, lasting {{c1::>3}} months• Heartburn, despite&n…
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Published 02/12/2024 **NON-PHARMACOLOGICAL THERAPY – Heartburn and DyspepsiaAvoid or limit offending food or beverage:• {{c1::Alcohol}}• {{c1::Caffeinated}}&nbsp…
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Published 02/12/2024 **Antacids• Use: {{c1::Mild, infrequent}} heartburn• {{c1::Neutralize gastric acid}} to relieve heartburn• Liquid formulation: {{c1::faster onset}} th…
Published 02/12/2024 **PATIENT EDUCATION – Antacids• Symptoms relief usually begins within {{c1::5}} minutes• Should not exceed {{c1::four times}} per day, or regular use …
Published 02/12/2024 **Bismuth Subsalicylate• Indication: {{c1::heartburn, upset stomach, indigestion, nausea, diarrhea, gas relating to overconsumption of food/drink}}• D…
Published 02/12/2024 **Histamine-2 Receptor Antagonists (H2RA)• Mechanism of Action: {{c1::Reversibly inhibits H2 receptors on parietal cells, inhibiting histamine re…
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Published 02/12/2024 **PATIENT EDUCATION – Histamine-2 Receptor Antagonists (H2RA)• {{c1::Mild to moderate and infrequent}} heartburn• Symptoms relief usually begins withi…
Published 02/12/2024 **Proton Pump Inhibitors (PPI)**• Mechanism of Action{{c1::: Irreversibly inhibits proton pumps (H+/ K+-ATPase) thatsecrete acid, blocking final …
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Published 02/12/2024 **PATIENT EDUCATION – PPI• Mild to moderate, frequent heartburn occurring {{c1::2 or more}} days per week• Take {{c1::1 tablet}} with {{c1::a gla…
Published 02/12/2024 Product SelectionDrugs to Avoid• H2RA and PPI: {{c1::Beer’s Criteria for Inappropriate Use in Older Patients}}• Aluminum- and magnesium- containing {{…
Published 02/12/2024 BACKGROUND AND DEFINITIONS – Intestinal Gas• Eructation: {{c1::belching of swallowed air}}• Bloating: {{c2::discomfort from stomach fullness or disten…
Published 02/12/2024 ETIOLOGY• Food or lifestyle• Lactose intolerance: {{c1::deficiency of lactase to break down lactose forabsorption}}• Lactase persistence trait• I…
Published 02/12/2024 Gas Producing Foods or Habits Food/Beverage ↑ gas production:{{c1::Lactose in dairy products}}• {{c2::Milk, cheese, ice cream}}{{c1::Fructose}}• {{c2:…
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Published 02/12/2024 **NON-PHARMACOLOGICAL THERAPY – Intestinal GasTarget Eating Habits• {{c1::Eat slowly, do not rush through meal• Do not overload stomach• Chew foo…
Published 02/12/2024 **Simethicone• Mixture of {{c1::inert silicon polymers}}• Used as {{c1::defoaming agent to decrease surface tension of gas bubbles in GI tract mu…
Published 02/12/2024 **Alpha-galactosidase• Enzyme from {{c1::Aspergillus niger mold}}• {{c1::Hydrolyzes oligosaccharides}} to be metabolized by colonic bacteria• Use{{c2:…
Published 02/12/2024 **Lactase Replacements• Enzyme breaks down lactose --> {{c1::galactose + glucose}}• Use: {{c1::prevention of gas, bloating, or diarrhea related to …
Published 02/12/2024 **Activated Charcoal• Use: {{c1::reduce malodor sulfur-based gas; not approved or shown to be efficacious to relieve intestinal gas}}• Dose: {{c2::520…
Published 02/12/2024 **PATIENT EDUCATION – Intestinal Gas ProductsSimethicone treats {{c1::intestinal gas that has formed}}• Simethicone is safe for {{c1::babies…
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