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Published 04/01/2024 A 65-year-old man presents to the emergency department with confusion. The patient was normal this morning, but during a hike with his friend, he bega…
Published 04/01/2024 A 50-year-old woman with a headache has abnormal findings on an axial susceptibility-weighted image. Which of the following tests would be associated …
Published 04/01/2024 A 74-year-old woman who has had Parkinson's disease for the past 10 years has been on increasing doses of carbidopa/levodopa for worsening rigidity an…
Published 04/01/2024 An 11-year-old boy with autism was found dead in bed. He had a long-standing history of uncontrolled generalized tonic-clonic seizures despite treatme…
Published 04/01/2024 A 28-year-old woman with a history of asthma and Raynaud phenomenon has been experiencing recurrent episodes of throbbing headache on one side, along …
Published 04/01/2024 An 8-month-old infant has a history of multiple sudden brief episodes of the arms flinging out, the knees pulling up, and the body bending forward. Hy…
Published 04/01/2024 A 30-year-old woman presents with a history of several episodes of extreme anxiety, sweating, and palpitations. Some of these episodes occurred while …
Published 04/01/2024 A 60-year-old man presents with a 4-month history of progressive proximal arm and leg weakness and dry mouth. Nerve conduction studies reveal normal s…
Published 04/01/2024 The first FDA-approved diagnostic imaging agent for differentiating Parkinson's disease from essential tremor relies on the binding of the radiopharma…
Published 04/01/2024 A 50-year-old man presents with a 2-year history of brief attacks of vertigo lasting several minutes. He has no history of hearing loss or tinnitus. O…
Published 04/01/2024 A patient with epilepsy has recurrent seizures characterized by tonic extension of the right upper extremity and abduction and flexion of the left upp…
Published 04/01/2024 A 26-year-old woman presents with a 2-day history of vision loss in the right eye. She describes her vision as if looking through a "smudged sunglasse…
Published 04/01/2024 A 32-year-old man presents with a 4-week history of progressively painful distal weakness in his arms and legs. He also reports symptoms of nausea, vo…
Published 04/01/2024 A 16-year-old boy is admitted to the pediatric ICU following a prolonged cardiac arrest. Over the course of several days, brainstem reflexes remain ab…
Published 04/01/2024 A 7-year-old boy presents with a 6-month history of progressive clumsiness and dysarthria. He has pes cavus, kyphoscoliosis, and a wide-based gait. He…
Published 04/01/2024 Which of the following genetic loci is an established risk factor for late-onset Alzheimer's disease? Amyloid precursor protein APOE epsilon 4 varian…
Published 04/01/2024 Which of the following oral triptans has the longest duration of action? eletriptan frovatriptan rizatriptan sumatriptan zolmitriptanCorrect Answer: …
Published 04/01/2024 Which of the following factors best helps distinguish an episode of syncope from cataplexy?Level of consciousnessDuration of eventLoss of motor streng…
Published 04/01/2024 When administered concurrently, which of the following antiseizure medications is most likely to significantly increase the blood level of lamotrigine…
Published 04/01/2024 An 11-year-old girl is experiencing frequent abnormal movements, as shown in the video. She feels a strong urge to make these movements but can only s…
Published 04/01/2024 A 24-year-old man presents with spontaneous development of acute pain on the right side of the neck and right shoulder. As the pain resolves over 10 d…
Published 04/01/2024 An infectious (mycotic) aneurysm is most likely to occur in which of the following arteries? Distal basilar artery Distal middle cerebral artery Proxi…
Published 04/01/2024 A 31-year-old woman presents with 3 days of progressive left lower extremity weakness and no history of back pain or trauma. On examination, there is …
Published 04/01/2024 Despite aggressive treatment with benzodiazepines and IV antiseizure medications, a patient remains in convulsive status epilepticus for 4 hours. At t…
Published 04/01/2024 A 55-year-old man, with a history of hypertension and a left basal ganglia hemorrhage 3 months ago, reports decreased coordination in the right hand, …
Published 04/01/2024 A 70-year-old woman presents with progressive ataxia and hearing loss. Gradient T2-weighted and axial FLAIR MRI scans are shown. Which of the followin…
Published 04/01/2024 A 60-year-old woman presents with left foot drop that developed after she sat with her legs crossed for an extended period of time. She has a history …
Published 04/01/2024 A 68-year-old man presents with right facial weakness for the past 3 days. Medical history reveals non-Hodgkin lymphoma for which he receives chemothe…
Published 04/01/2024 Autopsy is requested on a 62-year-old patient with autonomic dysfunction, cerebellar dysfunction, and parkinsonism. Axial and sagittal FLAIR sequence…
Published 04/01/2024 A 36-year-old woman taking tramadol for posttraumatic chronic low back pain and trazadone for insomnia presents following a first-ever generalized ton…
Published 04/01/2024 A 59-year-old woman who has a 10-year history of myasthenia gravis initially presented with a myasthenic crisis and required intubation. She is curren…
Published 04/01/2024 A 5-year-old girl presents with focal seizures with retained awareness, characterized by constant clonic jerking of the right index finger. Seizure fr…
Published 04/01/2024 A 43-year-old man with relapsing-remitting multiple sclerosis has been taking natalizumab for the past 5 years. Over the past several months, he has d…
Published 04/01/2024 A 68-year-old man admitted to the hospital with failure to thrive is constantly confused about his environment, barely speaks, has no recollection of …
Published 04/01/2024 A 24-year-old man has had severe headache for the past month. Examination reveals lens dislocation and papilledema. MRI scan shows cerebral venous sin…
Published 04/01/2024 An 80-year-old woman with hypertension is brought to the emergency department with acute onset of left-sided facial weakness and headache. On examinat…
Published 04/01/2024 A 55-year-old man presents with a 2-year history of persistent burning pain in his feet. Neurologic exam reveals normal strength, vibration sensation,…
Published 04/01/2024 The most sensitive indicator of small-fiber sensory neuropathy is a(n): A. Reduced sural nerve action potential amplitude. B. Reduced recruitment on n…
Published 04/01/2024 A 72-year-old man presents with 6 months of progressive gait difficulty, along with intermittent confusion, excessive daytime sleepiness, and episodic…
Published 04/01/2024 A 2-year-old child is evaluated for brief episodes of vertigo during which he clutches his parent and looks frightened. Episodes gradually abate witho…
Published 04/01/2024 A 3-year-old child is diagnosed with acute disseminated encephalomyelitis (ADEM). Myelin oligodendrocyte glycoprotein (MOG) antibodies are positive. A…
Published 04/01/2024 Which of the following interventions would be most beneficial for tics in a 12-year-old patient with Tourette syndrome?music therapyhabit reversal tra…
Published 04/01/2024 A 44-year-old patient with a history of gastric cancer treated with a gastrectomy has a 1-year history of progressively worsening imbalance and falls.…
Published 04/01/2024 A 20-year old-woman presents after a generalized tonic-clonic seizure. History includes a mild febrile illness with upper respiratory symptoms, follow…
Published 04/01/2024 A right-handed, 48-year-old man has been deaf since childhood and communicates predominantly by signing, but he can use spoken and written language. H…
Published 04/01/2024 A 48-year-old woman reports an inability to grip small objects with her left hand but has no sensory complaints. When asked to make a fist, she can fl…
Published 04/01/2024 The parents of a 7-year-old girl report she does not seem to listen, fails to finish tasks, loses things, is easily distracted and forgetful, and talk…
Published 04/01/2024 A 5-year-old girl is referred for evaluation of gait difficulty. The patient was delivered at term with no perinatal complications Gross motor develop…
Published 04/01/2024 A 10-year-old girl began having brief staring spells at age 5 years. Initial EEG is shown. She was started on a medication that stopped the episodes, …
Published 04/01/2024 A 72-year-old woman presents with a 2-year history of progressive difficulty using her left hand and frequent falls. Examination reveals bradykinesia …
Published 04/01/2024 Which of the following is the principal cerebral location for traumatic contrecoup contusions?A. beneath the site of impactB. corpus callosumC. bilate…
Published 04/01/2024 A 41-year-old woman with chronic migraine experiences cognitive impairment when taking topiramate and lightheadedness when taking propranolol. Her BMI…
Published 04/01/2024 A 20-year-old man is injured playing football. Needle EMG reveals denervation in the tibialis anterior, tibialis posterior, and tensor fascia latae. W…
Published 04/01/2024 A 24-year-old man presents with a history of frequent falls. He describes the episodes as being stereotyped union laughter and resulting in sudden and…
Published 04/01/2024 A 2-year-old boy has had seizures since age 9 months. Initially, most episodes were characterized by prolonged hemiclonic seizures that coincided with…
Published 04/01/2024 Which of the following disorders is the most common cause of neonatal seizures? bacterial meningitis benign neonatal familial convulsions hypoxic isch…
Published 04/01/2024  The combination of spongiosis and gliosis of the posterior columns and corticospinal tracts characterizes which of the following diseases? ALSan…
Published 04/01/2024  A 44-year-old woman with a new diagnosis of relapsing-remitting multiple sclerosis is to be treated with siponimod (fingolimod). Which of the fo…
Published 04/01/2024 Following a viral illness, a 26-year-old man reports the inability to sweat. This indicates involvement of which of thefollowing autonomic fibers?post…
Published 04/01/2024 Which of the following CS profiles is the most likely to predict functional decline and conversion from mild cognitiveimpairment to Alzheimer disease?…
Published 04/01/2024 A 45-year-old woman with multiple sclerosis decides she no longer wants to self-administer injections and transitions fromglatiramer acetate to dimeth…
Published 04/01/2024 GABAergic fibers are sent to the thalamus by which of the following basal ganglia structures?Caudate nucleusGlobus pallidus internaPutamenSubstantia n…
Published 04/01/2024 A 52-year-old woman sustains an infarct to the lateral medulla. The nucleus ambiguus is involved. Which of the following functions would be affected b…
Published 04/01/2024 A 64-year-old man presents with a 3-day history of severe left anterior thigh pain and left lower extremity weakness. He has a 10-year history of hype…
Published 04/01/2024 A 53-year-old man is admitted for treatment of dehydration after several days of vomiting and diarrhea due to a gastrointestinal infection. On arrival…
Published 04/01/2024 A 6-month-old female infant presents with small-amplitude, high-frequency, intermittent dysconjugate horizontal and vertical nystagmus, It increases d…
Published 04/01/2024 A 78-year-old woman with multiple-system atrophy is brought to the hospital by her family for failure to thrive. She lost 30 lb the patient has told t…
Published 04/01/2024 Aicardi syndrome is most frequently associated with which of the following clinical characteristics?ataxiahigh incidence of immune deficitsincreased r…
Published 04/01/2024 An 8-year-old boy reports trouble seeing and headaches. He asks his parents why his firetruck looks pink. There are no other systemic symptoms. Which …
Published 04/01/2024 A 25-year-old man who undergoes an appendectomy has neck spasms with involuntary neck extension 24 hours after surgery but no changes in awareness or …
Published 04/01/2024 Which of the following nerve conduction study/EMG findings would help differentiate multifocal motor neuropathy from ALS?conduction block in motor ner…
Published 04/01/2024 A 5-year-old girl began having seizures at 6 months of age, characterized by clonic jerking of one arm and leg and lasting longer than 10 minutes. At …
Published 04/01/2024 A 3-year-old girl has a history of normal development to 12 months after which time she began to lose milestones. She presents with an acquired microc…
Published 04/01/2024 A 4-month-old male infant has had several daily spells of body jerks for the past week. During the examination, hesuddenly flexes his body, neck, and …
Published 04/01/2024 A 73-year-old woman with a history of hypertension and diabetes mellitus presents with a sudden onset of vertigo, nausea, and vomiting. Her brain CT s…
Published 04/01/2024 The images shown are from a 78-year-old woman who presents with rigidity, progressive dementia, and weakness. These findings are most consistent with …
Published 04/01/2024 Which of the following is the most common side effect of adeno-associated virus vector-based gene therapy with onasemnogene abeparvovec for SMA?gastri…
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