Notes in Pharmacology

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Metabolism and Excretion

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Published	08/24/2024	Drugs and metabolites can move from the ___________.
Published	08/24/2024	Renal Excretion
Published	08/24/2024	Non-Renal Excretion examples
Published	08/24/2024	Drugs HAVE to be water-soluble to be excreted: Why?
Published	08/24/2024	3 processes of Renal Excretion:
Published	08/24/2024	Glomerular Filtration is dependent on 2 factors: _______ & ________
Published	08/24/2024	Glomerular filtration
Published	08/24/2024	________= Movement of molecules from circulation → into the tubular filtrate. This process can be passive or active.
Published	08/24/2024	Tubular secretion: Passive diffusion & Active secretion
Published	08/24/2024	________=  Movement of molecules from filtrate, back into circulation
Published	08/24/2024	Tubular reabsorption: Passive and Active reabsorption
Published	08/24/2024	Tubular Reabsorption: Bromide
Published	08/24/2024	Renal Excretion: key points of each:Glomerular FiltrationSecretionReabsorption
Published	08/24/2024	Drug Plasma Protein Binding summary
Published	08/24/2024	Drug Plasma Protein Binding: XP and X
Published	08/24/2024	Equilibrium reaction is influenced by:
Published	08/24/2024	Highly Plasma Protein Bound drugs...
Published	08/24/2024	Cefovecin (Convenia): Example
Published	08/24/2024	Tubular Reabsorption example: Furosemide
Published	08/24/2024	Diuretic
Published	08/24/2024	Metabolism of drugs/metabolites summary
Published	08/24/2024	Phase I reactions
Published	08/24/2024	Phase II Reactions
Published	08/24/2024	Phase II reactions are either:
Published	08/24/2024	Species differences in Metabolic enzymes includes:
Published	08/24/2024	Cats and Paracetamol Clinical signs and abnormalities.
Published	08/24/2024	Cats and Paracetamol Potential Treatments.
Published	08/24/2024	Dogs and Paracetamol
Published	08/24/2024	CYP Enzyme Inhibitors and Inducers: examples
Published	08/24/2024	Strategies to circumvent first pass metabolism:
Published	08/24/2024	Enterohepatic Circulation
Published	08/24/2024	In plasma protein binding, An equilibrium reaction is affected by....
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