Notes in BIOC 405

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Status	Last Update	Fields
Published	11/06/2023	Advantages of bringing multiple proteins together
Published	11/06/2023	Point Symmetry
Published	11/06/2023	n fold symmetry
Published	11/06/2023	What type of symmetry is this?
Published	11/06/2023	What type of symmetry is this?
Published	11/06/2023	Tetrahedral Symmetry (vertex, face, and edge symmetry?)
Published	11/06/2023	Icosahedral Symmetry (vertex, face, and edge symmetry?)
Published	11/06/2023	Octahedral Symmetry (vertex, face, and edge symmetry?)
Published	11/06/2023	How many subunits in a given icosahedral symmetric virus?
Published	11/06/2023	Helical Symmetry
Published	11/06/2023	G-Actin Structure
Published	11/06/2023	Cholera toxin (Vibrio cholorae) and Enterotoxin (enterotoxigenic E. coli) Components?
Published	11/06/2023	What is this and what type of symmetry does it have?
Published	11/06/2023	Most abundant cytosolic protein in eukaryotic cells?
Published	11/06/2023	Polymer made of globular actin? Symmetry?
Published	11/06/2023	Virus with helical symmetry from lecture?
Published	11/06/2023	Symmetry in the Nucleosome
Published	11/06/2023	What enzyme helps with the formation of disulfide bonds?
Published	11/06/2023	PDI start and end form when disulfides are incorrectly connected?
Published	11/06/2023	PDI start and end form when disulfides have not been formed?
Published	11/06/2023	What is the fxn of HSP70? (Chaperone Protein)
Published	11/06/2023	What is the fxn of Chaperonin GroEL/GroES? (Chaperone Protein)
Published	11/06/2023	GroEL/GroES chaperone symmetry?
Published	11/06/2023	How many molecules of ATP are used to refold a protein in GroEL/GroES Chaperonin?
Published	11/06/2023	What are amyloids?
Published	11/06/2023	Amyloids involved with Alzheimer's Disease?
Published	11/06/2023	Myoglobin Structure
Published	11/06/2023	Binding of oxygen to make oxy-myoglobin
Published	11/06/2023	Myoglobin "Heme complex"
Published	11/06/2023	Oxygen Binding Curve shape of Myoglobin
Published	11/06/2023	What is the oxygen transporter in the blood of most animals?
Published	11/06/2023	Hemoglobin structure
Published	11/06/2023	Oxygen Binding Curve of Hemoglobin
Published	11/06/2023	T-state Hemoglobin
Published	11/06/2023	R-state Hemoglobin
Published	11/06/2023	Oxygen binding to heme in Hb
Published	11/06/2023	What is the P50 value of a dissociation curve?
Published	11/06/2023	Efficiency of Oxygen delivery
Published	11/06/2023	Why does Hb-O2 binding have sigmoidal curve?
Published	11/06/2023	Bohr effect on oxygen delivery by Hb
Published	11/06/2023	Symmetric Allostery of Hb
Published	11/06/2023	Sequential Allostery of Hb
Published	11/06/2023	How does BPG (D-2,3-Bisphosphoglycerate) affect O2-Hb binding?
Published	11/06/2023	[BPG] in RBCs and p50 at sea level
Published	11/06/2023	[BPG] in RBCs and p50 at high altitude adaptation
Published	11/06/2023	What is the oxygen binding protein in blue blood of mollusks and arthropods?
Published	11/06/2023	Structure of Mollusk hemocyanins
Published	11/06/2023	Structure of Arthropod hemocyanins
Published	11/06/2023	What is this structure and what kind of symmetry does it have?
Published	11/06/2023	What coordinates O2 bining in hemocyanin?
Published	11/06/2023	"Normal" Hb genotype
Published	11/06/2023	Sickle cell anemia Hb genotype
Published	11/06/2023	Cause of Sickle Cell Anemia?
Published	11/06/2023	How does β1-β2 interxn affect RBCs? (SCA)
Published	11/06/2023	Why is HbS so common?
Published	11/06/2023	What can kinetics tell us about a system?
Published	11/06/2023	What is half life?
Published	11/06/2023	What does free energy (ΔG) tell us about the reaction rate?
Published	11/06/2023	What is ΔG0‡?
Published	11/06/2023	Does an enzyme lower activation energy in forward or reverse direction?
Published	11/06/2023	How do enzymes shift reaction rates?
Published	11/06/2023	How can you use enzyme kinetics to understand a system?S -> P
Published	11/06/2023	What is one assumption that must made to calculate the kinetics of an enzyme-catalyzed reaction?
Published	11/06/2023	What is the Michaelis-Menten Equation?
Published	11/06/2023	What is Km?
Published	11/06/2023	What is Vmax?
Published	11/06/2023	Lineweaver-Burk Plot eqn
Published	11/06/2023	What can be obtained from Lineweaver-Burk plot?
Published	11/06/2023	What is Ki?
Published	11/06/2023	What is competitive inhibition?
Published	11/06/2023	What are some key functions of biological membranes?
Published	11/06/2023	What are the building blocks of biological membranes?
Published	11/06/2023	What kind of double bonds are found in the hydrocarbon chains of fatty acids?
Published	11/06/2023	What is the pKa of a fatty acid carboxyl head group?
Published	11/06/2023	What does 18:1(Δ9) mean when referring to a fatty acid?
Published	11/06/2023	What is the omega carbon of a fatty acid?What is omega notation?
Published	11/06/2023	How does hydrocarbon chain length affect the melting point of fatty acids?
Published	11/06/2023	How do double bonds affect the melting point of fatty acids?
Published	11/06/2023	What is Triacylglycerol?
Published	11/06/2023	What makes triacylglycerols (fats) a good form of energy storage?
Published	11/06/2023	How does the state of a liquid depend on fatty acid composition?
Published	11/06/2023	What are membrane lipids composed of?
Published	11/06/2023	What is PE? (Hint: Glycerophospholipid)
Published	11/06/2023	What is PC? (Hint: Glycerophospholipid)
Published	11/06/2023	What is PS? (Hint: Glycerophospholipid)
Published	11/06/2023	What is PI? (Hint: Glycerophospholipid)
Published	11/06/2023	What is a cardiolipin?
Published	11/06/2023	What is the function of cardiolipin?
Published	11/06/2023	What is a sphingolipid?
Published	11/06/2023	What class of sphingolipids are similar to phosphoglycerides (contain phosphate in head group)?
Published	11/06/2023	What class of sphingolipids had a single sugar head group?
Published	11/06/2023	What are gangliosides?
Published	11/06/2023	What is the purpose of gangliosides?
Published	11/06/2023	The metabolism of what molecule is altered in the development of Tay-Sachs disease?
Published	11/06/2023	What are the components of cholesterol?
Published	11/06/2023	What are the components of steroids?
Published	11/06/2023	What drives the self-association of Lipids?
Published	11/06/2023	Self association of amphipathic lipids:
Published	11/06/2023	What shape do single fatty-acyl chains, like detergents, form?
Published	11/06/2023	What are the fundamentals of the fluid mosaic model of membrane organization?
Published	11/06/2023	How can lateral diffusion be measured in a bilayer?
Published	11/06/2023	How does temp relative to Tm affect fluidity of a membrane?
Published	11/06/2023	How are membrane fluidity and Tm  affected by short and unsaturated fatty acid chains?
Published	11/06/2023	How are membrane fluidity and Tm  affected by long and saturated fatty acid chains?
Published	11/06/2023	What effect does temperature have on bacterial membrane composition?
Published	11/06/2023	How do eukaryotes use cholesterol to regulate memrane fluidity?
Published	11/06/2023	What molecules does cholesterol associate with in a membrane?
Published	11/06/2023	What are lipid rafts composed of?
Published	11/06/2023	What functionality do lipid rafts provide?
Published	11/06/2023	Asymmetric distribution of membrane bilayers? (Inner/Outer)
Published	11/06/2023	What protein facilitates transverse diffusion of lipids?
Published	11/06/2023	What is the function of a floppase?
Published	11/06/2023	What phospholipid transporter facilitates transverse diffusion without using ATP?
Published	11/06/2023	What percentage of the genome encodes membrane proteins?
Published	11/06/2023	What is the protein content of a typical membrane?
Published	11/06/2023	Where are integral membrane proteins found?
Published	11/06/2023	How can integral membrane proteins be separated from the membrane?
Published	11/06/2023	Where are peripheral membrane proteins found?
Published	11/06/2023	How can peripheral membrane proteins be separated from the bilayer?
Published	11/06/2023	What is the most common membrane spanning motif for integral membrane proteins?
Published	11/06/2023	Can proteins have multiple membrane spanning helices?
Published	11/06/2023	What motif is commonly found in transporter, pore, and channel membrane proteins?
Published	11/06/2023	How can transmembrane helices be identified analytically?
Published	11/06/2023	What are annular lipids and what do they do?
Status	Last Update	Fields