Notes in PTH.S1.L15.Diseases of the Central Nervous System

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Name
Cellular Pathology of CNS
Cerebrovascular Disease
Demyelinating diseases and Neurodegenerative diseases
Genetic Metabolic Diseases
Malformation & Devt of Disorders and Trauma
Tissue Adaptations of CNS
Toxic and Acquired Metabolic Diseases
Tumors

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Published	12/09/2024	1. Which of the following is the most common cause of acute pyogenic meningitis in neonates?A) N. meningitidisB) S. pneumoniaeC) E. coliD) L. monocyto…
Published	12/09/2024	In acute pyogenic meningitis, what is typically observed in CSF analysis?A) Lymphocytic pleocytosisB) Neutrophilic predominanceC) Normal glucose level…
Published	12/09/2024	Which of the following is a common complication of acute pyogenic meningitis?A) Meningococcal syndromeB) Waterhouse-Friderichsen syndromeC) Tabes dors…
Published	12/09/2024	Which organism is commonly associated with acute aseptic meningitis?A) N. meningitidisB) EnterovirusesC) Streptococcus pneumoniaeD) Klebsiella
Published	12/09/2024	What is the hallmark feature of CSF in chronic bacterial meningitis due to tuberculosis?A) Lymphocytic pleocytosisB) Markedly reduced glucoseC) Elevat…
Published	12/09/2024	Which organism is most commonly responsible for brain abscesses?A) Cryptococcus neoformansB) Candida albicansC) Streptococcus and StaphylococcusD) Asp…
Published	12/09/2024	Which of the following is the characteristic diagnostic finding in rabies encephalitis?A) Microglial nodulesB) Negri bodies in neuronsC) Oligodendrocy…
Published	12/09/2024	Which fungal agent is most frequently associated with chronic meningitis in immunocompromised patients?A) Aspergillus fumigatusB) Mucor speciesC) Cand…
Published	12/09/2024	In which condition do patients commonly present with cognitive impairment and mood alterations progressing to severe dementia (general paresis)?A) Neu…
Published	12/09/2024	10. Which parasitic infection can lead to rapidly fatal necrotizing encephalitis, particularly in immunocompromised individuals?A) Toxoplasma gondiiB)…
Published	12/09/2024	Most common route of spread is through the blood, but {{c1::directimplantation from trauma}} or {{c1::congenital malformation}}, localextension, …
Published	12/09/2024	Acute Pyogenic Meningitis● Neonates→ {{c1::E. coli}}→ {{c1::GBS}}
Published	12/09/2024	Acute Pyogenic Meningitis● Elderly→ {{c1::S. pneumoniae}}→ {{c1::L. monocytogense}}
Published	12/09/2024	Acute Pyogenic Meningitis● Adolescents, young adults→ {{c1::N. meningitidis}}● Immunosuppressed→ {{c2::Klebsiella}}→ {{c2::Anaerobes}}
Published	12/09/2024	Tuberculosis● May be part of active TB elsewhere in the body or appear in isolation● Most common pattern: {{c1::meningoencephalitis}}
Published	12/09/2024	Tuberculosis● Most serious complications→ {{c1::Arachnoid fibrosis}}    May lead to {{c4::hydrocephalus}}→ {{c3::Obliterative endarteritis}}…
Published	12/09/2024	Neurosyphilis● {{c1::Tertiary::Secondary or Tertiary}} stage of syphilis
Published	12/09/2024	Negri bodies→ {{c1::Cytoplasmic}}, round, {{c1::oval}}, eosinophilic inclusions found in the pyramidal neurons of the hippocampus and purkinje cells i…
Published	12/09/2024	The principal functional unit of the CNS is the {{c1::neuron}}
Published	12/09/2024	Clinical signs and symptoms following injury depend not only on the pathologic process but also on the {{c1::region of the brain affected}}
Published	12/09/2024	Mature neurons {{c1::CANNOT::can or cannot}} undergo cell division
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